How to populate values inside a new column based values from other columns in a dataframe in Pandas

I have dataframe df has shown below.

  df
DATA ELEMENT    PORT    LOCATION    P_RISK  S_RISK  W_RISK  Total_Risk
Event 1000     SGSIN                      0       0       0       0
Event 2000     MYKUL                      0       1       0       1
Event 3000                PARIS           0       0       1       1
Event 4000                LYON            1       0       0       1
Event 1000     USNYK                      0       0       0       0
Event 2000     INCOK                      0       0       1       1
Event 3000                MUMBAI          0       0       0       0
Event 4000                LAHORE          1       0       0       1
Event 2000     INCOK                      0       0       0       0
Event 3000                PARIS           0       0       0       0

Condition

*If Data Element is 1000 or 2000 and Total Risk is 1 then populate the new column comment with the With `Risk Name + PORT

*If Data Element is 3000 or 4000 and Total Risk is 1 then populate the new column comment with the With Risk Name + LOCATION

*If Total Risk is 0 then populate No Risk Indentified

Expected Output

df
    DATA ELEMENT    PORT    LOCATION    P_RISK  S_RISK  W_RISK  Total_Risk  Comment
    Event 1000     SGSIN                      0       0       0       0     No Risk Indentified
    Event 2000     MYKUL                      0       1       0       1     S_RISK  predicted at  MYKUL
    Event 3000                PARIS           0       0       1       1     W_RISK predicted at  PARIS
    Event 4000                LYON            1       0       0       1     P_RISK  predicted at  LYON
    Event 1000     USNYK                      0       0       0       0     No Risk Indentified
    Event 2000     INCOK                      0       0       1       1     W_RISK predicted at  INCOK
    Event 3000                MUMBAI          0       0       0       0     No Risk Indentified
    Event 4000                LAHORE          1       0       0       1     P_RISK  predicted at  LAHORE
    Event 2000     INCOK                      0       0       0       0     No Risk Indentified
    Event 3000                PARIS           0       0       0       0     No Risk Indentified

How can this be done?