How do I check if a file is present in a particular location?

I would just like help writing my if statement, I am having a hard time finding information online to do what I would like. Basically I need my if statement to see if the $file is located at a specified location (which can be multiple locations if possible). So far I have this:

foreach ($file in $MyInvocation.MyCommand.Path) {
  if ($file) {  #I need this to search a specific directory or directories
  }
}