How to keep a specif column based on row conditions?

Does someone knows how to get the next followed structure in Pandas?

I have a Pandas data frame that looks like this

ID  VAR1  VAR2  VAR3  VAR4  VAR5

1    TT    TG    .01  .09   .90
2    CC    TC    .20  .34   .56
3    GG    AG    .10  .20   .70
4    TC    TC    .17  .48   .35
5    AG    AG    .12  .46   .32
6    GG    TG    .15  .20   .65
7    TT    TC    .06  .24   .70
8    TT    CT    .11  .21   .68 
9    GT    GT    .05  .10   .85

1. If the first 'letter' in [VAR2] (e.g T) it is doubled in [VAR1] (e.g. TT) -> take value from VAR3 (.01).
2. If the combination of the letters in [VAR2] (e.g. TC) it is the same as in [VAR1] (e.g. TC) -> take value from VAR4 (.48).
3. If the second 'letter' in [VAR2] (e.g G) it is doubled in [VAR1] (e.g GG) -> take value from VAR5 (.70).

Based on this information I would like my output data frame to look as follow:

ID  VAR1  VAR2   VAR6 

1    TT    TG    .01
2    CC    TC    .56
3    GG    AG    .70
4    TC    TC    .48
5    AG    AG    .46
6    GG    TG    .65
7    TT    TC    .06
8    TT    CT    .68
9    GT    GT    .10

Hopefully someone can give me a hint!

Thanks,

Ale.