If statement with conditions

Is there any way to make the following if statement more elegant without the need to repeat the "and" conditional ? Sorry I m a newbie.

a = ' 10 20 30 40 50  '
print(a)
if '10' and '20' and '30' and '40' and '50' not in a :
    print('something is wrong')
else:
    print('This is correct')

Thanks