How can I avoid a million if statements? Python

So i'm really new to python and anyways I wanted to do my own projects, I'm trying to make a small grading system right now. This is how I'm doing it at the moment, I wanted to ask for any better ways I can do this to avoid to many if statements. Please keep in mind I'm really new, I've been coding in python for only a few months.

A = "A"
B = "B"
C = "C"
D = "D"
F = "F"

Josh = [D, B]
Jack = [F, D]
Steve = [C, B]

program = "running"

while program == "running":
  question = input("Type [1] to view the kids grades \n\nType [2] to change them!\n")

  if question == "1":
    print(f"\n{Josh}\n{Jack}\n{Steve}\n")

  if question == "2":
    who = input("\nWho do you want to change?\n")
    if who == "Josh":
      grade = input("\nFirst grade to change:\n")
      if grade == "A":
        Josh[0] = A
      if grade == "B":
        Josh[0] = B
      if grade == "C":
        Josh[0] = C
      if grade == "D":
        Josh[0] = D
      if grade == "F":
        Josh[0] = F

if program == "stop":
  print("Shutting down.")