Reverse inequality statement

If you multiply an inequality by a negative number you must reverse the direction of the inequality.

For example:

• 1 < x < 6 (1)
• -1 > -x > -10 (2)

if x = 6, it is consistent with equation (1) and (2).

Is there a way to multiply an inequality statement by an integer in a one-liner for Python to reverse the signs?

From the practical point of view, I am trying to extract DNA/protein sequences from TBLASTN results. There are strands +1 and -1 and the operation after that condition statement is the same.

# one-liner statement I would like to implement
if (start_codon <= coord <= stop_codon)*strand:
    # do operation

# two-liner statement I know would work
if (start_codon <= coord <= stop_codon) and strand==1:
    # do operation
elif (start_codon >= coord >= stop_codon) and strand==-1:
    # do operation