AI multiple input conversation with if statements in while loop doesn't work?

My AI i am making works in a while loop there are if statements for everything i want it to say for example:

`while 1:



lis = ("im bored","game","im board","what do you want to do","what should we do","rage","i","I","smashed","broke","destroyed","cracked","grounded","detention","in trouble","nothing","not much","erics number","date","time","no","nope","nah","not","yes","yep","yeah","in deed","bye","gtg","got to go","see you","c u","hi","hello","hello","hia","fuck","crap","shit","bleep","omg","OMG","oh my god","","","","","","look up","email","map","add Note","get Note","joke","rabid donkey","game","quit","help","raging","hurt","fire","","thanos","erics mad","danger","sad","upset","","","creator","thanks","lol","ok","k","yep","report","owner","maker","jarvis","coder","thank you","sup","whats up","what's up","hey","hah")

resp2 = input("")

esa = ""
for word in lis:
    if word in resp2:
       esa = word

    if esa in ("quit","bye","gtg","got to go","see you","c u"):
            byebro = random.choice(("ok bye Sergei cu later","bye sir","c u later sir","talk to you later then","talk to you later"))
            print (byebro)
            os.system("say '"+byebro+"'")
            exit()

    if esa in ("look up","web search","search the web for"):

            c = random.choice(("ok","lets see","let me see","ok sir il get right on that lets see","im looking up and i dont see anything??"))
            print (c)
            c1 = ("sorry an error has acurred package missing")
            print (c1)

            os.system("say '"+c+"'")
            os.system("say '"+c1+"'")
            break


    if esa == "add note":
            d = random.choice(("ok sir one sec il pull up the note pad","ok sir one sec","yeah one sec il pull it up","one sec sir","ok","ok sir"))
            print (d)
            os.system("say '"+d+"'")
            note1 = input("")
            notes.append(note1)
            break

    if esa == "get note":
            e = random.choice(("ok sir one sec il pull up the your recent notes","ok sir one sec","yeah one sec il pull it up","one sec sir","ok","ok sir notes","ok sir"))
            print (e)
            os.system("say '"+e+"'")

ok so there are hundreds of these if statements but i want to be able to talk to jarvis like this. where i can say something and then he will ask me about it then i will answer then he answers then it breaks out of the if statement and goes through the loop and all the if statements again.

me: i am grounded jarvis

jarvis: what did you do?

me: i smashed a window

jarvis: oh ok

so i want the code to look like this but it doesn't work

if esa in ("im grounded","im in trouble","i got detention"):
    print "your always getting in trouble its like second nature to you"
    esa3 = input("what did you do")
if esa3 in ("i broke something","i smashed something"):
    print "your always breaking stuff"